2025

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Previous news

01/01/2025: Congratulations to Lianjia Li on being awarded the runner-up at the Final of the 2024 Campus Top 10 Singers Competition of the University of Chinese Academy of Sciences (2024年中国科学院大学校园十佳歌手大赛).

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

05/05/2025: Congratulation to Dong Ding for winning the Best Research Report Award (最佳研究报告奖) at the 21st Graduate Research Review Appreciation Day (GRAD,研究生科研工作赏评日) event held at the Shanghai Institute of Nutrition and Health, CAS, and for receiving the Outstanding Graduates of Shanghai Ordinary Colleges and Universities (上海市普通高等学校优秀毕业生).

 

 

 

 

  • 2018-05-18
    2017
  • 2018-05-18
    2016
  • 2018-05-18
    2015
  • 2018-05-18
    2014
  • 2018-05-18
    2013
  • 2019-05-21
    2018

03/27/2025: Dr. Yu Li was invited to give a talk entitled “FGF21 positively regulates PPP6C to attenuate metabolic dysfunction-associated steatohepatitis” at the 2025 Cold Spring Harbor Asia Conferences: Liver Metabolism, Inflammation, and Cancer, Suzhou, China.

  • 2020-09-04
    2019

06/18/2025: Drs. Yu Li and Aoyuan Cui were invited to give oral presentations at the 16th CADA Annual Meeting, Chicago, IL, USA.

06/21/2025: Dr. Yu Li was invited to give an oral presentation entitled “PPP6C Mediates FGF21 Action on Hepatic Lipid Metabolism and Metabolic Dysfunction-Associated Steatohepatitis via Directly Dephosphorylating TSC2”, and Dr. Aoyuan Cui was invited to give an oral presentation entitled “Posttranslational Modification of Adipose Tissue Aging and Metabolic Dysregulation by the Methyltransferase SETD2” at the 85st Scientific Sessions of American Diabetes Association, Chicago, IL, USA.

  • 2023-01-15
    2021

05/13/2025: Congratulation to PhD degree graduation for Dong Ding and Zengpeng Zheng. Congratulation to master degree graduation for Xiaoyi Wei. Thank all the thesis defense committee members. Wishing them a bright future!

05/30/2025: Congratulation to Lianjia Li, Zhan Liu and Xiaoyi Wei for receiving the Merit Student Award (三好学生).

 

08/15/2023: Dr. Yu Li was invited to participate in the closed-door roundtable of the 3rd Frontier Symposium on Clinical and Basic Research of Metabolic Diseases 2025, which is organized by Division of Metabolism affiliated to the Chinese Society of Biochemistry and Molecular Biology (CSBMB), Chengdu.

  • 2021-09-10
    2020
  • 2023-01-16
    2022

 

06/06/2025: The launch meeting of the National Science and Technology Major Project for Noncommunicable Chronic Diseases, entitled "Identification of novel cell subtypes regulating glucose and lipid metabolism and their roles in the pathogenesis of metabolic diseases", was held in Shanghai. Dr. Yu Li elaborated on the overall project progress and laid out a detailed plan for subsequent work to ensure the project will be completed with high quality. Thank all participating experts for their careful guidance and insightful comments.

02/11/2025: Congratulation to Drs. Zhengshuai Liu, Shuang Wei and Yang Jiang for the publication of the article entitled “Protein phosphatase 6 regulates metabolic dysfunction-associated steatohepatitis via the mTORC1 pathway” in Journal of Hepatology (2025, 83(3):630-642). In multiple preclinical and clinical studies, fibroblast growth factor 21 (FGF21) analogs have shown therapeutic promise for MASH. This study identifies that PPP6C acts as a direct target of FGF21 signals in regulating MASH development and reveals the biological function of hepatic PPP6C in alleviating MASH progression.

Dr. Morris J. Birnbaum from University of Pennsylvania, USA published a highly complimentary editorial entitle “A newly revealed signaling pathway may explain the conundrum of how FGF21 simultaneously increases insulin sensitivity and autophagy” in Journal of Hepatology (2025, 83(3):609-610) on the our paper, highlighting the following key points: 1) FGF21 inhibits mTORC1 by activating PPP6C to regulate lysosomal function, and exerts a dual effect of enhancing insulin sensitivity and inducing autophagy in hepatocytes simultaneously. 2) This dual effect of FGF21 confers an evolutionary advantage: the living conditions of human ancestors constantly exposed the liver to various stimuli, which induce the expression and secretion of FGF21 to protect the liver and adapt to the uncertainty of food availability.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  • 2024-12-27
    2023

 

08/21/2025: Dr. Yu Li was invited to give a talk entitled “A novel mechanism of FGF21 treatment for MASH mediated by protein phosphatase PPP6C”, and Linghao Xu was invited to give an oral presentation entitled “The joint effect of a body shape index and remnant cholesterol inflammatory index (RCII) on incident cardiovascular diseases and the mediating role of RCII in Chinese adults: a nationwide prospective cohort study” at the 22st Annual Meeting of Chinese Society of Endocrinology (CSE), Chongqing.

 

08/25/2025: Li Lab attended the 8th Research Conference of Metabolic Biology Society affiliated to Biophysical Society of China, Wenzhou.

 

09/10/2025: Happy Teachers’ Day! Thank you for the blessings from students around the world.

 

10/19/2025: Haokai Yu and Yang Jiang participated in the Semi-Ironman Triathlon held in Shanghai Bay Area(上海湾区半程铁人三项赛). Yang Jiang completed the race in 1 hour 43 minutes, ranking 14th in his age group, while Haokai Yu finished in 1 hour 42 minutes, ranking 11th place in his age group.

 

10/23/2025: Congratulation to Zhan Liu, Lianjia Li and Shuang Wei for receiving the National Scholarship (国家奖学金).

 

11/20/2025: Dr. Yu Li was invited to attend and give a talk entitled “FGF21 as a Therapeutic Target in MASH: Unraveling the Molecular Mechanisms” at the Chinese Diabetes Association (CDS)’s 27th scientific meeting in Xi’an.

 

 

 

11/22/2025: Linghao Xu was invited to give an oral presentation entitled “Interactive and combined effects of body roundness index and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio on diabetes mellitus and the mediating effects of TG/HDL-C in middle-aged and elderly adults: A nationwide prospective cohort study” at the 27th Scientific Meeting of the Chinese Diabetes Society (中华医学会糖尿病学分会第二十七次学术会议),Shanxi.

 

 

 

12/09/2025: Congratulation to Linghao Xu for receiving the First Prize of the Southwest Medical University Doctoral Institute Academic Scholarship(博士研究生学业奖学金) and the Outstanding Student Award (优秀学生).

 

 

12/13/2025: Mengyao Huang participated in the “Keyuan Cup” (科苑杯) badminton tournament organized by the UCAS and achieved good results.

 

12/20/2025: The Lilab team embarked on a rejuvenating and immersive team-building journey to Kota Kinabalu (亚庇), the vibrant capital of Sabah, Malaysia (马来西亚・沙巴). This five-day retreat masterfully blended awe-inspiring natural encounters with rich cultural experiences, fostering deeper bonds and creating unforgettable shared memories under the Borneo sun.

Day 1: Serene Arrival and Golden Horizons

The adventure began with the team's arrival on December 14th. After checking in, they headed straight to the historic Kota Kinabalu Cafe (哥打京那巴鲁咖啡馆) to sample authentic laksa (叻沙) , immersing themselves in the local flavors. Following the meal, they explored the lively morning market (早市) , taking in the bustling atmosphere and local produce. Then, the first stop was the stunning Floating Mosque (水上清真寺) , its magnificent structure perfectly mirrored in the lagoon, instilling a sense of peace. A leisurely citywalk through bustling local markets followed, filled with the enticing aromas of street food. The day culminated at Tanjung Aru Beach (丹绒亚路海滩) for a breathtaking sunset. As the sky melted into hues of orange and purple, the team shared a moment of collective awe, warmly welcomed by Sabah's golden hour.

Day 2: Island Paradise and Underwater Wonders

Day two was dedicated to island hopping (跳岛游) to the pristine Mantanani Island (环滩岛) . The excitement built during the speedboat ride across the sparkling sea. The journey was enlivened by the crew's infectious singing, which got some team members joining in, though a few others felt a bit seasick from the choppy waves. The main activity, snorkeling (浮潜) , revealed a vibrant underwater world. Swimming alongside colorful schools of fish, the team was filled with childlike wonder and exhilaration, their laughter echoing above the crystal-clear waters. In the evening, the team sought out Ang Restaurant (洪金买饭店) for a taste of local Bak Kut Teh (肉骨茶) . However, the experience was underwhelming, as the dish turned out to be rather average.

Day 3: Cultural Immersion and Magical Nightlights

The focus shifted to heritage on day three at the Mari-Mari Cultural Village (马里马里文化村) . Here, the team immersed themselves in the rich traditions of Sabah's diverse ethnic groups, including the Kadazan-Dusun (卡达山-杜顺族), Lundayeh (伦达耶族), Murut (慕鲁族), Bajau (巴夭族), and Rungus (龙古斯族) . The team actively participated in traditional activities, from fire-starting to blowpipe shooting (吹箭) and even getting temporary tribal tattoos (纹身). They also enjoyed sampling local delicacies and joined in lively cultural dances, sparking curiosity and joyous interaction as they experienced the unique customs of each group. As evening approached, the team gathered on a nearby beach for a bonfire (篝火) , where they sang and danced under the twilight sky, adding a festive touch to the night. Then, a cruise through the Kawa Kawa Mangrove Forest (红树林) offered tranquility. The true highlight came after dark: thousands of fireflies (萤火虫) transformed the trees into a twinkling fairyland, leaving the team in spellbound silence under the starry sky.

Day 4: Twin Island Adventure and Coastal Thrills

Another day of exploration took the team to the popular twin islands of Sapi Island (沙比岛) and Manukan Island (马努干岛) . The mood was energetic and playful. Some sought adrenaline through parasailing (拖曳伞) , soaring high with exhilarating shouts, while others enjoyed swimming and sunbathing on the soft white sands. The easy access between islands made for a day full of shared fun and relaxation. As night fell, the team headed to a local seafood market (海鲜市场) to feast on fresh catches, savoring the flavors of the sea and reflecting on the day's adventures.

Day 5: Highland Majesty and a Tranquil Finale

The final day presented a dramatic change of scenery. A visit to the Desa Cattle Dairy Farm (奶牛牧场) in the foothills of Mount Kinabalu offered a taste of alpine freshness, with cool air and rolling green pastures. Following the farm visit, they stopped at Gerai Pekan Nabalu (拿巴鲁集市) , a local market offering handicrafts and snacks, adding a cultural touch to the highland experience. The journey then continued with an inspiring hike in the Kinabalu National Park (神山公园) . Walking through the ancient, mossy forest, the team felt a profound sense of peace and accomplishment. After the hike, they explored the nearby Botanical Garden (植物园) , admiring the diverse flora of Borneo, a perfect end to their adventure surrounded by the majesty of nature.

A Journey of Shared Discovery

This expedition to Kota Kinabalu was more than a retreat; it was a collective narrative of discovery. From the serene waters of the mosque to the glittering mangrove nights, and from vibrant coral reefs to misty mountain trails, every experience strengthened the team's unity. Lilab returns reinvigorated, bound together like a family, carrying with them the shared spirit of adventure and a renewed commitment to collaboration.

Lilab2023 Christamas Party vlog

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

http://www.bilibili.com/video/BV13p421U7FA/?vd_source=3f0920246f173da4c9d953578b9652fc

Lilab2024 Christamas Party vlog

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

http://www.bilibili.com/video/BV13p421U7FA/?vd_source=3f0920246f173da4c9d953578b9652fc

Lilab2025 Teacher's Day vlog

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

http://www.bilibili.com/video/BV13p421U7FA/?vd_source=3f0920246f173da4c9d953578b9652fc

 

12/31/2025: Congratulation to Lianjia Li on advancing to the final of the 2025 Campus Top 10 Singers Competition of the University of Chinese Academy of Sciences and on retaining the Top 10 Singer title (十佳歌手称号) for the second consecutive year.

 

  • 2026-03-14
    2024

2026

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

01/30/2026: Lab family gathered together to congratulate our two couples - Weitong Su & Sihao Gu, Dong Ding & Jiayu Chen - on their happy marriage, wishing them a long life together as they step into a new chapter of life.

 

 

02/08/2026: Congratulation to Linghao Xu on being awarded the 2025 Outstanding PhD Student by the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan.

 

08/31/2025: Congratulations to Dr. Jiang Yang on the approval of his applications for the National Natural Science Foundation of China Young Scientist Fund (Category C), the Shanghai Natural Science Foundation Young Scientist Program, the China Postdoctoral Science Foundation General Program, and the Chinese Academy of Sciences Special Research Assistant Funding Program.

 

29/09/2025: Dr. Jiang Yang was invited to participate in the 2025 Physiology and Integrative Biology Youth Forum organized by the Department of Life Sciences of the National Natural Science Foundation of China in Beijing, where he gave a presentation titled "Mechanisms of Hepatic Lipid Metabolic Homeostasis Regulation and Metabolic Dysfunction-Associated Steatotic Liver Disease."